NEOADJUVANT THERMOCHEMORADIOTHERAPY USING INTRARECTAL 5-FLUORURACIL IN COMBINED TREATMENT OF RECTAL CANCER

Yu. A. Barsukov; Барсуков Ю. А.; S. I. Tkachev; Ткачев С. И.; N. D. Oltarzhevskaya; Олтаржевская Н. Д.; D. V. Kuzmichev; Кузьмичев Д. В.; Z. Z. Mamedli; Мамедли З. З.; A. M. Pavlova; Павлова А. М.; A. G. Malikhov; Малихов А. Г.; E. N. Kholyavka; Холявка Е. Н.

doi:10.17650/2220-3478-2013-0-1-11-18

NEOADJUVANT THERMOCHEMORADIOTHERAPY USING INTRARECTAL 5-FLUORURACIL IN COMBINED TREATMENT OF RECTAL CANCER

Authors: Barsukov Y.A.¹, Tkachev S.I.¹, Oltarzhevskaya N.D.¹, Kuzmichev D.V.¹, Mamedli Z.Z.¹, Pavlova A.M.¹, Malikhov A.G.¹, Kholyavka E.N.¹
Affiliations:
1. N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Issue: Vol 2, No 1 (2013)
Pages: 11-18
Section: IN FOCUS
Published: 28.02.2015
URL: https://onco-surgery.info/jour/article/view/41
DOI: https://doi.org/10.17650/2220-3478-2013-0-1-11-18
ID: 41

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Abstract

Safety and efficacy of intrarectal 5-fluoruracil in combined treatment of localized rectal cancer was investigated in this article. Our data supports safety, economical efficacy and simplicity of use of this method. It improves sphincter preservation rate in patients with distal rectal cancer, does not increase surgical mortality and morbidity, leads to high tumor regression rate, improves local control and decreases distant failure rate.