MICROBIOTA, IMMUNE SYSTEM AND COLORECTAL CANCER

E. P. Kharchenko; Харченко Е. П.; I. A. Solov’ev; Соловьев И. А.

doi:10.17650/2220-3478-2017-7-4-11-19

MICROBIOTA, IMMUNE SYSTEM AND COLORECTAL CANCER

Authors: Kharchenko E.P.¹, Solov’ev I.A.²
Affiliations:
1. I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences
2. S.M. Kirov Military Medical Academy, Ministry of Defense of Russia
Issue: Vol 7, No 4 (2017)
Pages: 11-19
Section: LITERATURE REVIEW
Published: 27.02.2018
URL: https://onco-surgery.info/jour/article/view/230
DOI: https://doi.org/10.17650/2220-3478-2017-7-4-11-19
ID: 230

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Abstract

The article briefly considers physiological aspects of the human gut microbiota, associations between dysbiosis and colorectal cancer (CRC), disturbance of immune system in CRC, mechanisms of avoidance of immune surveillance by tumors, genetic instability in CRC, collisions and perspective of immunotherapy of CRC.