Email this article Endoscopic diagnosis and treatment of a patient with synchronous rectal neuroendocrine tumors (a case report)
- Authors: Malikhova O.A.1, Karasev I.A.1, Lozovaya V.V.1, Vereshchak V.V.1
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Affiliations:
- N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
- Issue: Vol 9, No 3 (2019)
- Pages: 59-61
- Section: CASE REPORT
- Published: 30.09.2019
- URL: https://onco-surgery.info/jour/article/view/297
- DOI: https://doi.org/10.17650/2220-3478-2019-9-3-59-61
- ID: 297
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Abstract
In this article, we describe the procedure of comprehensive endoscopic diagnostics and treatment of a patient with synchronous rectal neuroendocrine tumors. The patient underwent screening colonoscopy at the age of 44; a year before, he had an immunochromatographic fecal occult blood test, which was negative. At the first stage, we performed narrow band imaging with optical magnification, chromoscopy using indigo carmine dye, and endosonography with a 12 MHz transducer. Then the patient underwent radical endoscopic mucosal resection with submucosal dissection. Immunohistochemical examination of surgical specimens demonstrated that both tumors were well differentiated (G1 ). The patient was followed up during a year and had no signs of recurrence.
About the authors
O. A. Malikhova
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Email: fake@neicon.ru
24 Kashirskoe Shosse, Moscow 115478.
Russian FederationI. A. Karasev
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Author for correspondence.
Email: ronc-karasev@yandex.ru
24 Kashirskoe Shosse, Moscow 115478.
Russian FederationV. V. Lozovaya
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Email: fake@neicon.ru
24 Kashirskoe Shosse, Moscow 115478.
Russian FederationV. V. Vereshchak
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Email: fake@neicon.ru
24 Kashirskoe Shosse, Moscow 115478.
Russian FederationReferences
- Ramage J.K., de Herder WW., Delle Fave G. et al. ENETS Consensus Guidelines Update for Colorectal Neuroendocrine Neoplasms. Neuroendocrinology 2016;103(2):139—43.
- Qi Z.-P., Shi Q., Liu J.-Z. et al. Efficacy and safety of endoscopic submucosal dissection for submucosal tumors of the colon and rectum. Gastrointest Endosc 2018;87(2):540—8.
- Bolzacchini E., Chini C., Cortelezzi C.C. et al. Poorly differentiated neuroendocrine carcinoma of the sigmoid tract in long-standing ulcerative colitis: report of a case and review of the literature. Int J Surg Pathol 2018;26(5):479—83.
- Kojima M., Ikeda K., Saito N. et al. Neuroendocrine tumors of the large intestine: clinicopathological features and predictive factors of lymph node metastasis. Front Oncol 2016;6:173. doi: 10.3389/fonc.2016.00173.
- Nitsche U., Stogbauer F., Spath C. et al. Right sided colon cancer as a distinct histopathological subtype with reduced prognosis. Dig Surg 2016;33(2):157—63. doi: 10.1159/000443644.
- Woischke C., Schaaf C.W., Yang H.-M. et al. In-depth mutational analyses of colorectal neuroendocrine carcinomas with adenoma or adenocarcinoma components. Mod Pathol 2016;30(1):95—103.
- Oronsky B., Ma P.C., Morgensztern D., Carter C.A. Nothing but NET: a review of neuroendocrine tumors and carcinomas. Neoplasia 2017;19(12):991-1002. doi: 10.1016/j.neo.2017.09.002.
- Komatsubara T., Koinuma K., Miyakura Y. et al. Endocrine cell carcinomas of the colon and rectum: a clinicopathological evaluation. Clin J Gastroenterol 2016;9(1):1—6. doi: 10.1007/s12328-015-0623-6.
- Kokubo S., Ohnuma S., Suzuki H. et al. A small neuroendocrine tumor of less than 5 mm with lymph node metastasis. Gan To Kagaku Ryoho 2018;45(13): 1985-7.
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