Email this article Irinotecan in the treatment of colorectal cancer. A literature review
- Authors: Ivanov V.A.1, Gordeev S.S.2, Baychorov, A.B.2, Aliev V.A.2, Kuz’michev D.V.2, Polynovskiy A.V.2, Rasulov A.O.2
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Affiliations:
- ФГБУ «Российский онкологический научный центр им. Н. Н. Блохина» Минздрава России
- N. N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia
- Issue: Vol 7, No 1 (2017)
- Pages: 46-56
- Section: REVIEW
- Published: 10.04.2017
- URL: https://onco-surgery.info/jour/article/view/203
- DOI: https://doi.org/10.17650/2220-3478-2017-7-1-46-56
- ID: 203
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Abstract
In 1998, oncologists got a brand new antitumor drug – irinotecan. It’s been already 18 years since its approval for second-line polychemotherapy of metastatic colorectal cancer. Indications for irinotecan use were significantly expanded since that time; it is now used in combination with other therapeutic agents for first- or second-line treatment of metastatic colorectal cancer, in combination with targeted drugs or separately; there are some studies assessing the use of irinotecan in neoadjuvant therapy. The article describes the history and modern schemes of irinotecan administration in treatment of colorectal cancer.
About the authors
V. A. Ivanov
ФГБУ «Российский онкологический научный центр им. Н. Н. Блохина» Минздрава России
Email: fake@neicon.ru
Хирургическое отделение № 3 (онкопроктологии) Минздрава России; Россия, 115478 Москва, Каширское шоссе, 23
Russian FederationS. S. Gordeev
N. N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia
Author for correspondence.
Email: ss.netoncology@gmail.com
Surgical Department No 3 (Coloproctology), 23 Kashirskoe Shosse, Moscow 115478, Russia
Russian FederationA. B. Baychorov,
N. N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia
Email: fake@neicon.ru
Surgical Department No 3 (Coloproctology), 23 Kashirskoe Shosse, Moscow 115478, Russia Russian Federation
V. A. Aliev
N. N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia
Email: fake@neicon.ru
Surgical Department No 3 (Coloproctology), 23 Kashirskoe Shosse, Moscow 115478, Russia Russian Federation
D. V. Kuz’michev
N. N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia
Email: fake@neicon.ru
Surgical Department No 3 (Coloproctology), 23 Kashirskoe Shosse, Moscow 115478, Russia Russian Federation
A. V. Polynovskiy
N. N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia
Email: fake@neicon.ru
Surgical Department No 3 (Coloproctology), 23 Kashirskoe Shosse, Moscow 115478, Russia Russian Federation
A. O. Rasulov
N. N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia
Email: fake@neicon.ru
Surgical Department No 3 (Coloproctology), 23 Kashirskoe Shosse, Moscow 115478, Russia Russian Federation
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