Surgery and OncologySurgery and OncologyХирургия и онкология2949-5857Publishing House ABV Press9410.17650/2220-3478-2013-0-3-27-31REVIEWОБЗОРЫ ЛИТЕРАТУРЫTHE COMPLETE PATHOMORPHOLOGICAL RESPONSE TO NEOADJUVANT THERAPY AND ITS ROLE IN THE TREATMENT STRATEGY FOR RECTAL CANCERПОЛНЫЙ ПАТОМОРФОЛОГИЧЕСКИЙ ОТВЕТ НА НЕОАДЪЮВАНТНУЮ ТЕРАПИЮ И ЕГО РОЛЬ В СТРАТЕГИИ ЛЕЧЕНИЯ РАКА ПРЯМОЙ КИШКИKarachunA. M.КарачунА. М.
Russian Federation
dr.a.karachun@gmail.comSinenchenkoG. I.СиненченкоГ. И.
Russian Federation
dr.a.karachun@gmail.comSamsonovD. V.СамсоновД. В.
Russian Federation
dr.a.karachun@gmail.comAliyevI. I.АлиевИ. И.
Russian Federation
dr.a.karachun@gmail.comN.N. Petrov Research Institute of Oncology, Ministry of Health of Russia, Saint PetersburgФГБУ «Научно-исследовательский институт онкологии им. Н.Н. Петрова» Минздрава России, Санкт-ПетербургS.M. Kirov Military Medical Academy, Ministry of Defense of Russia, Saint PetersburgФГКВОУ ВПО «Военно-медицинская академия им. С.М. Кирова» Минобороны России, Санкт-Петербург270920132327310103201501032015Copyright ©; 2013, Karachun A.M., Sinenchenko G.I., Samsonov D.V., Aliyev I.I.Copyright ©; 2013, Карачун А.М., Синенченко Г.И., Самсонов Д.В., Алиев И.И.2013Karachun A.M., Sinenchenko G.I., Samsonov D.V., Aliyev I.I.Карачун А.М., Синенченко Г.И., Самсонов Д.В., Алиев И.И.https://creativecommons.org/licenses/by/4.0https://onco-surgery.info/jour/article/view/94

The therapeutic strategy in rectal cancer has substantially changed in the past decade. Total mesorectumectomy has been widely used. Many specialized health facilities have accepted radio/chemoradiotherapy for locally advanced rectal cancer as a standard. At the same time as high as one quarter of the patients receiving neoadjuvant therapy demonstrate a complete pathomorphological regression of a tumor. In this connection, the current literature discusses whether medical treatment is permissible in this group of patients.

В последние десятилетия лечебная стратегия в отношении рака прямой кишки (РПК) существенно изменилась. Повсеместное распространение получила тотальная мезоректумэктомия. Лучевая/химиолучевая терапия местно-распространенного РПК принята в качестве стандарта многими специализированными лечебными учреждениями. При этом до четверти пациентов, получивших неоадъювантную терапию, демонстрируют полный патоморфологический регресс опухоли. В связи с этим в современной литературе обсуждается вопрос о допустимости консервативной тактики в отношении указанной категории больных.

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