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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Surgery and Oncology</journal-id><journal-title-group><journal-title xml:lang="en">Surgery and Oncology</journal-title><trans-title-group xml:lang="ru"><trans-title>Хирургия и онкология</trans-title></trans-title-group></journal-title-group><issn publication-format="electronic">2949-5857</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">799</article-id><article-id pub-id-type="doi">10.17650/2949-5857-2025-15-4-53-59</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>ORIGINAL REPORT</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Efficacy of endoscopic mucosal resection of colorectal laterally spreading tumors</article-title><trans-title-group xml:lang="ru"><trans-title>Эффективность эндоскопической резекции слизистой оболочки при латерально стелющихся образованиях толстой кишки</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0313-5504</contrib-id><name-alternatives><name xml:lang="en"><surname>Faizulina</surname><given-names>R. R.</given-names></name><name xml:lang="ru"><surname>Файзулина</surname><given-names>Р. Р.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>christinataranets@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4803-4157</contrib-id><name-alternatives><name xml:lang="en"><surname>Nuzova</surname><given-names>O. B.</given-names></name><name xml:lang="ru"><surname>Нузова</surname><given-names>О. Б.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>christinataranets@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-6850-5467</contrib-id><name-alternatives><name xml:lang="en"><surname>Taranets</surname><given-names>K. O.</given-names></name><name xml:lang="ru"><surname>Таранец</surname><given-names>К. О.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>christinataranets@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.I. Pirogov Orenburg City Clinical Hospital</institution></aff><aff><institution xml:lang="ru">ГАУЗ «Городская клиническая больница им. Н.И. Пирогова»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Orenburg State Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Оренбургский государственный медицинский университет» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2025-12-21" publication-format="electronic"><day>21</day><month>12</month><year>2025</year></pub-date><volume>15</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>53</fpage><lpage>59</lpage><history><date date-type="received" iso-8601-date="2025-06-15"><day>15</day><month>06</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, ABV-press</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, АБВ-пресс</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">ABV-press</copyright-holder><copyright-holder xml:lang="ru">АБВ-пресс</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://onco-surgery.info/jour/about/editorialPolicies</ali:license_ref></license></permissions><self-uri xlink:href="https://onco-surgery.info/jour/article/view/799">https://onco-surgery.info/jour/article/view/799</self-uri><abstract xml:lang="en"><p><bold>Background.</bold> Colorectal laterally spreading tumor (LST) is a large and relatively flat neoplasm more than 10 mm in diameter, growing laterally to the intestinal wall. Endoscopy plays a major role in the diagnosis and treatment of LST.</p> <p><bold>Aim.</bold> To study the efficacy of endoscopic mucosal resection of colorectal laterally spreading tumors.</p> <p><bold>Materials and methods.</bold> A retrospective analysis of the results of endoscopic mucosal resection of LST performed between 2020 and 2023 at the Center of Coloproctology of Orenburg Region State Hospital No. 2 was performed. Hot-snare <italic>en bloc</italic> and piecemeal endoscopic mucosal resections (EMR) were performed.</p> <p><bold>Results.</bold> In the course of the study, we have analyzed 1,762 endoscopic resections of colon neoplasms, of which LST removal was performed in 99 (5.61 %) cases in 87 patients. EMR <italic>en bloc</italic> was performed in 23 (23.2 %) cases. Piecemeal EMR was performed in 76 (76.8 %) cases. There were no mortalities. Four (4) (4.04 %) complications were recorded. In 6 (12.2 %) cases out of 49 patients studied, residual lesions were detected at the control colonoscopy after 6 months.</p> <p><bold>Conclusion.</bold> Endoscopic mucosal resection is an effective and accessible method of minimally invasive resection of colorectal laterally spreading tumors.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Введение.</bold> Латерально стелющиеся образования (ЛСО) толстой кишки представляют собой большие и относительно плоские новообразования &gt; 10 мм в диаметре, растущие в латеральном направлении по отношению к стенке кишечника. Основную роль в диагностике и лечении ЛСО играет эндоскопия.</p> <p><bold>Цель исследования</bold> – изучение эффективности применения эндоскопической резекции слизистой оболочки для удаления ЛСО толстой кишки.</p> <p><bold>Материалы и методы.</bold> Выполнен ретроспективный анализ всех проведенных в колопроктологическом центре Оренбургской областной клинической больницы № 2 в 2020–2023 гг. удалений ЛСО методом эндоскопической резекции слизистой оболочки (endoscopic mucosal resection, EMR). Операцию осуществляли «горячей» петлей единым блоком, а также пофрагментарно.</p> <p><bold>Результаты.</bold> В рамках исследования проанализированы 1762 случая EMR толстой кишки, удаление ЛСО проведено в 99 (5,61 %) из них у 87 пациентов. Единым блоком операция проведена в 23 (23,2 %) случаях, пофрагментарно – в 76 (76,8 %). Летальность отсутствовала. Зафиксировано 4 (4,04 %) осложнения. На контрольной колоноскопии через 6 мес у 6 (12,2 %) из 49 исследованных пациентов обнаружены резидуальные образования.</p> <p><bold>Выводы.</bold> EMR является эффективным и доступным методом, позволяющим проводить минимально инвазивные вмешательства по поводу колоректальных ЛСО.</p></trans-abstract><kwd-group xml:lang="en"><kwd>laterally spreading tumors</kwd><kwd>endoscopic mucosal resection</kwd><kwd>colonoscopy</kwd><kwd>colorectal cancer</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>латерально стелющееся новообразование</kwd><kwd>эндоскопическая резекция слизистой оболочки</kwd><kwd>колоноскопия</kwd><kwd>колоректальный рак</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Zhao X., Zhan Q., Xiang L. et al. Clinicopathological characteristics of laterally spreading colorectal tumor. PLoS One 2014;9(4):e94552. 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