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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Surgery and Oncology</journal-id><journal-title-group><journal-title xml:lang="en">Surgery and Oncology</journal-title><trans-title-group xml:lang="ru"><trans-title>Хирургия и онкология</trans-title></trans-title-group></journal-title-group><issn publication-format="electronic">2949-5857</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">752</article-id><article-id pub-id-type="doi">10.17650/2949-5857-2024-14-4-11-19</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>DESCRIPTION OF THE METHODOLOGY</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОПИСАНИЕ МЕТОДОЛОГИИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Mapping during morphological study of samples of laterally spreading colon neoplasia after endoscopic submucosal dissection</article-title><trans-title-group xml:lang="ru"><trans-title>Картирование при морфологическом изучении образцов латерально распространяющихся неоплазий толстой кишки после эндоскопической подслизистой диссекции</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5262-4953</contrib-id><name-alternatives><name xml:lang="en"><surname>Setdikova</surname><given-names>G. R.</given-names></name><name xml:lang="ru"><surname>Сетдикова</surname><given-names>Г. Р.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><bold>Galiya R. Setdikova </bold></p><p>Department of Fundamental Medical Disciplines, Faculty of Medicine, State University of Education</p><p><italic>61/12 Shchepkin St., Moscow 129110, </italic></p><p><italic>Bld 2, 10 A Radio St., Moscow 105005</italic></p></bio><bio xml:lang="ru"><p><bold>Галия Равилевна Сетдикова </bold></p><p>Кафедра фундаментальных медицинских дисциплин, медицинский факультет ФГАОУ ВО «Государственный университет просвещения»</p><p><italic>129110 Москва, ул. Щепкина, 61/12,</italic></p><p><italic>105005 Москва, ул. Радио, 10 А, стр. 2</italic></p><p> </p></bio><email>galiya84@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0831-0973</contrib-id><name-alternatives><name xml:lang="en"><surname>Verbovsky</surname><given-names>A. N.</given-names></name><name xml:lang="ru"><surname>Вербовский</surname><given-names>А. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>61/12 Shchepkin St., Moscow 129110</italic></p></bio><bio xml:lang="ru"><p><italic>129110 Москва, ул. Щепкина, 61/12</italic></p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7365-6081</contrib-id><name-alternatives><name xml:lang="en"><surname>Semenkov</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Семенков</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Oncology, Radiotherapy and Reconstructive Surgery,<italic> </italic>I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia</p><p><italic>61/12 Shchepkin St., Moscow 129110, </italic></p><p><italic>Bld. 1, 6 Pirogovskaya St., Moscow 119992</italic></p></bio><bio xml:lang="ru"><p>Кафедра онкологии, радиотерапии и реконструктивной хирургии ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России</p><p><italic>129110 Москва, ул. Щепкина, 61/12,</italic></p><p><italic>119992 Москва, ул. Б. Пироговская, 6, стр. 1</italic></p></bio><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Moscow Regional Research and Clinical Institute</institution></aff><aff><institution xml:lang="ru">ГБУЗ МО «Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">State University of Education</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО «Государственный университет просвещения»</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2024-11-30" publication-format="electronic"><day>30</day><month>11</month><year>2024</year></pub-date><volume>14</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>11</fpage><lpage>19</lpage><history><date date-type="received" iso-8601-date="2024-11-29"><day>29</day><month>11</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2024-11-29"><day>29</day><month>11</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Setdikova G.R., Verbovsky A.N., Semenkov A.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Сетдикова Г.Р., Вербовский А.Н., Семенков А.В.</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Setdikova G.R., Verbovsky A.N., Semenkov A.V.</copyright-holder><copyright-holder xml:lang="ru">Сетдикова Г.Р., Вербовский А.Н., Семенков А.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://onco-surgery.info/jour/article/view/752">https://onco-surgery.info/jour/article/view/752</self-uri><abstract xml:lang="en"><p><bold>Introduction.</bold> According to the literature, the detection rate of laterally spreading tumors has increased in recent years due to the constant development of endoscopic diagnosis and treatment technologies. It is reported that these neoplasms account for about 15 % of all colorectal neoplasias. According to the literature, laterally spreading tumors are characterized by a more frequent presence of areas of malignancy compared to polypoid formations. Since such neoplasms are closely correlated with colorectal cancer, it is very important to fully understand the clinical presentation and morphological characteristics to select the optimal treatment strategy.</p><p><bold>Aim.</bold> The development of mapping of samples during morphological examination with subsequent correlation with endoscopic data and search for the most suitable areas for taking a biopsy.</p><p><bold>Materials and methods.</bold> To solve the problem described above, a mapping technology was developed for the morphological study of samples of laterally spreading colon neoplasia, which consists in creating an algorithm of actions, described in more detail in the work.</p><p><bold>Results.</bold> The first step of gross is the correct orientation of the resected specimen. The macroscopic integrity of the removed specimen is described. When describing microscopic data, the first question that the morphologist must answer is whether the process is benign or malignant. In case of malignant processes, the morphologist must answer according to the questionnaire: histological type, degree of differentiation / dysplasia, size (mm), depth of invasion, assessment of resection margins, lymphovascular and perineural invasion, tumor kidneys.</p><p><bold>Conclusion.</bold> The presented technique, when used in everyday pathological practice for neoplastic neoplasms of the colon, can allow a reliable assessment of all prognostic factors and the development of an objective interdisciplinary consensus for further treatment.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Введение.</bold> Согласно данным литературы, процент обнаружения латерально распространяющихся новообразований увеличился в последние годы благодаря постоянному развитию эндоскопической диагностики и лечебных технологий. Известно, что данные новообразования составляют около 15 % от всех колоректальных неоплазий. Для латерально распространяющихся опухолей характерно более частое наличие участков озлокачествления по сравнению с полиповидными образованиями. Поскольку такие новообразования тесно коррелируют с колоректальным раком, очень важно полностью понять клиническую картину и морфологические характеристики для выбора оптимальной тактики лечения.</p><p><bold>Цель исследования</bold> – разработка картирования образцов при морфологическом исследовании с последующей корреляцией с эндоскопическими данными и поиск наиболее подходящих участков для взятия биопсии.</p><p><bold>Материалы и методы.</bold> Для решения вышеописанной проблемы была разработана технология картирования при морфологическом изучении образцов латерально распространяющихся неоплазий толстой кишки, заключающаяся в создании алгоритма действий, более подробно изложенного в работе.</p><p><bold>Результаты.</bold> Начальным этапом макроскопического исследования является правильная ориентация резецированного образца. Описывается макроскопическая целостность удаленного образца. Далее описываются макроскопические параметры опухоли: отношение к краям резекции, размер, наличие полиповидных участков. При описании микроскопических данных первый вопрос, на который должен ответить морфолог, – это доброкачественный или злокачественный процесс. При злокачественных процессах морфологу необходимо ответить согласно опроснику: гистологический тип, степень дифференцировки / дисплазии, размер (мм), глубина инвазии, оценка краев резекции, лимфоваскулярная и периневральная инвазия, опухолевые почки.</p><p><bold>Заключение.</bold> Представленная методика при использовании в повседневной патологоанатомической практике при неопластических новообразованиях толстой кишки может позволить достоверно оценить все прогностические факторы и выработать объективный междисциплинарный консенсус дальнейшего лечения.</p></trans-abstract><kwd-group xml:lang="en"><kwd>epithelial tumor of the colon</kwd><kwd>endoscopic submucosal dissection</kwd><kwd>cancer in situ</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>эпителиальная опухоль толстой кишки</kwd><kwd>эндоскопическая подслизистая диссекция</kwd><kwd>рак in situ</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. 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