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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Surgery and Oncology</journal-id><journal-title-group><journal-title xml:lang="en">Surgery and Oncology</journal-title><trans-title-group xml:lang="ru"><trans-title>Хирургия и онкология</trans-title></trans-title-group></journal-title-group><issn publication-format="electronic">2949-5857</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">510</article-id><article-id pub-id-type="doi">10.17650/2686-9594-2021-11-2-49-54</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>LITERATURE REVIEW</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Cervical cancer in the Russian Federation and the risks of vaginal fistula</article-title><trans-title-group xml:lang="ru"><trans-title>Рак шейки матки в РФ и риски формирования вагинальных свищей</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Saryev</surname><given-names>M. N.</given-names></name><name xml:lang="ru"><surname>Сарыев</surname><given-names>М. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Mukhammetsakhet Nurberdievich Saryev</p><p>4 Kashirskoe Shosse, Moscow 115478</p></bio><bio xml:lang="ru"><p>Мухамметсахет Нурбердиевич</p><p>115478 Москва, Каширское шоссе, 24</p></bio><email>mishamoff@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Valiev</surname><given-names>R. K.</given-names></name><name xml:lang="ru"><surname>Валиев</surname><given-names>Р. К.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>86 Shosse Entuziastov, Moscow 111123</p></bio><bio xml:lang="ru"><p>111123 Москва, шоссе Энтузиастов, 86</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nechushkin</surname><given-names>M. I.</given-names></name><name xml:lang="ru"><surname>Нечушкин</surname><given-names>М. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>4 Kashirskoe Shosse, Moscow 115478</p></bio><bio xml:lang="ru"><p>115478 Москва, Каширское шоссе, 24</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nurberdyev</surname><given-names>M. B.</given-names></name><name xml:lang="ru"><surname>Нурбердыев</surname><given-names>М. Б.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>86 Shosse Entuziastov, Moscow 111123</p></bio><bio xml:lang="ru"><p>111123 Москва, шоссе Энтузиастов, 86</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Panichenko</surname><given-names>I. V.</given-names></name><name xml:lang="ru"><surname>Паниченко</surname><given-names>И. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>4 Kashirskoe Shosse, Moscow 115478</p></bio><bio xml:lang="ru"><p>115478 Москва, Каширское шоссе, 24</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tizilova</surname><given-names>E. A.</given-names></name><name xml:lang="ru"><surname>Тизилова</surname><given-names>Е. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>4 Kashirskoe Shosse, Moscow 115478</p></bio><bio xml:lang="ru"><p>115478 Москва, Каширское шоссе, 24</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н. Н. Блохина» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">A.S. Loginov Moscow Clinical Scientific Center of the Moscow Healthcare Department</institution></aff><aff><institution xml:lang="ru">ГБУЗ г. Москвы «Московский клинический научно-практический центр им. А. С. Логинова Департамента здравоохранения г. Москвы</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2021-11-28" publication-format="electronic"><day>28</day><month>11</month><year>2021</year></pub-date><volume>11</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>49</fpage><lpage>54</lpage><history><date date-type="received" iso-8601-date="2021-11-28"><day>28</day><month>11</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-11-28"><day>28</day><month>11</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2021, ABV-press</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2021, АБВ-пресс</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="en">ABV-press</copyright-holder><copyright-holder xml:lang="ru">АБВ-пресс</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://onco-surgery.info/jour/about/editorialPolicies</ali:license_ref></license></permissions><self-uri xlink:href="https://onco-surgery.info/jour/article/view/510">https://onco-surgery.info/jour/article/view/510</self-uri><abstract xml:lang="en"><p><bold>This review aims</bold> to provide up-to-date information on the factors associated with an increased risk of vaginal fistula in women with cervical cancer, as well as on methods of their prevention and treatment. It includes data on various types of vaginal fistulas in cervical cancer patients and risk factors for their development, according to foreign and Russian research articles published over the last 20 years. Cervical cancer is one of the most challenging oncological diseases in the Russian Federation, because it is detected at stage III–IV in more than 30 % of women. Such a high incidence of cervical cancer and the need for radiotherapy determine high risk of fistulas, which significantly impairs the quality of life. Thus, identification of factors associated with vaginal fistulas, as well as methods of their prevention and treatment remains a highly relevant task for the Russian healthcare system.</p></abstract><trans-abstract xml:lang="ru"><p>Целью работы является предоставление актуальной информации о факторах, ассоциированных с развитием вагинальных свищей на фоне рака шейки матки, а также о методах их профилактики и лечения. Обзор содержит данные о различных видах вагинальных свищей у больных раком шейки матки и факторах риска формирования свищей, полученные из зарубежных и российских научных статей по теме, опубликованных за последние 20 лет. Рак шейки матки для нашей страны является одной из значимых онкологических патологий, так как заболевание выявляется на III–IV стадии более чем у 30 % женщин. Такое распространение само по себе, как и необходимость проведения лучевой терапии, определяет высокий риск развития свищей, что значимо ухудшает качество жизни пациенток. Следовательно, поиск факторов, ассоциированных с развитием вагинальных свищей, а также методов профилактики и лечения – по-прежнему актуальная задача для нашей страны.</p></trans-abstract><kwd-group xml:lang="en"><kwd>cervical cancer</kwd><kwd>vaginal fistula</kwd><kwd>urogenital fistula</kwd><kwd>rectovaginal fistula</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак шейки матки</kwd><kwd>вагинальные свищи</kwd><kwd>урогенитальные свищи</kwd><kwd>ректовагинальные свищи</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>WHO Handbook for health inequality monitoring. Available at: https://www.who.int/gho/health_equity/handbook/en/.</mixed-citation></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">Malignant tumors in Russia in 2019. (incidence and mortality). Ed. by A.D. Kaprin, V.V. Starinskiy, A.O. Shakhzodova. Moscow: P.A. 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