Surgery and Oncology

Хирургия и онкология

2949-5857

Publishing House ABV Press

493

10.17650/2686-9594-2021-11-1-28-34

ORIGINAL REPORT

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ

Features of treatment rare forms of stromal cell ovarian tumors

Особенности лечения редких форм стромально‑клеточных опухолей яичников: серия клинических наблюдений

https://orcid.org/0000-0003-4915-2219

Beishembaev

A. М.

Бейшембаев

А. М.

Kyrgyzstan

144а Bokonbaeva St., Bishkek 720064

Алмаз Мукашевич Бейшембаев

720064 Бишкек, ул. Боконбаева, 144а

almazyaka@yandex.com

Kyrgyz State Medical Institute of Advanced Training and Retraining named after S.B. Daniyarov, Ministry of Health of Kyrgyz RepublicКыргызский государственный медицинский институт переподготовки и повышения квалификации им. С.Б. Даниярова Министерства здравоохранения Кыргызской Республики

02062021

111

28340106202101062021

2021

ABV-press

АБВ-пресс

https://onco-surgery.info/jour/about/editorialPolicies

https://onco-surgery.info/jour/article/view/493

Objective: identification and description of clinical and morphological characteristics of rare forms of stromal cell tumors of the ovaries.Materials and methods. Retrospectively processed over 10 thousand case histories of patients with various ovarian tumors who were examined and treated at the N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia and the National Center for Oncology and Hematology of the Ministry of Health of Kyrgyz Republic. In 473 patients were diagnosed stromal cell tumors, among them 3 cases of rare forms of tumors of the stroma of the sex cord were identified: stromal tumor from Sertoli cells, malignant luteoma of the ovary, lipid‑cell tumor from Leydig cells. All patients underwent a planned morphological study of surgical material and immune-histochemical study.Results. The detailed data of clinical observations of rare types of tumors, which was presented in the literature by isolated cases, are presented, the description of which in the literature is presented by isolated cases. The possible effect of clinical and morphological characteristics on the survival of patients with rare forms of stromal cell tumors of the ovaries were analyzed.Conclusions. The necrobiotic changes in the tumor, the degree of malignancy, and the stage of the disease are potential predictors of poor prognosis in patients with rare forms stromal cell tumors of the ovaries which require confirmation in a larger sample of patients.

Цель исследования – выявить и описать клинико‑морфологические особенности редких форм стромально‑ клеточных опухолей яичников (СКОЯ).Материалы и методы. Представлена серия клинических наблюдений, выявленных при анализе 473 историй болезней пациенток с СКОЯ, которые проходили обследование и лечение в ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Министерства здравоохранения России и Национальном центре онкологии и гематологии Министерства здравоохранения Кыргызской Республики. Было выявлено 3 случая редких форм опухолей стромы полового тяжа: стромальная опухоль из клеток Сертоли, злокачественная лютеома яичника, липидно‑клеточная опухоль из клеток Лейдига. Всем пациенткам были проведены плановое морфологическое исследование операционного материала и иммуногистохимическое исследование.Результаты. Приведены подробные данные клинических наблюдений редких форм СКОЯ, описание которых в литературе представлено единичными случаями. Анализируется возможное влияние клинико‑морфологических особенностей опухолей на выживаемость пациенток с редкими формами СКОЯ.Выводы. Вероятными предикторами неблагоприятного прогноза у пациенток с редкими формами СКОЯ являются наличие некробиотических изменений в опухоли, степень злокачественности и стадия заболевания, что требует подтверждения на большей выборке больных.

ovarian stromal cell tumorsmalignant ovarian luteomaLeydig cell tumorovarian cancer

стромально‑клеточные опухоли яичниковзлокачественная лютеома яичниковопухоль из клеток Лейдигарак яичников

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