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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Surgery and Oncology</journal-id><journal-title-group><journal-title xml:lang="en">Surgery and Oncology</journal-title><trans-title-group xml:lang="ru"><trans-title>Хирургия и онкология</trans-title></trans-title-group></journal-title-group><issn publication-format="electronic">2949-5857</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">37</article-id><article-id pub-id-type="doi">10.17650/2220-3478-2012-0-1-31-34</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>CASE REPORT</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">A RARE CASE OF TREATMENT POLICY FOR RECURRENT NEUROENDOCRINE CARCINOMA OF THE ANAL CANAL</article-title><trans-title-group xml:lang="ru"><trans-title>РЕДКОЕ НАБЛЮДЕНИЕ И ТАКТИКА ЛЕЧЕНИЯ РЕЦИДИВА НЕЙРОЭНДОКРИННОГО РАКА АНАЛЬНОГО КАНАЛА</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Barsukov</surname><given-names>Y. A.</given-names></name><name xml:lang="ru"><surname>Барсуков</surname><given-names>Ю. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kim</surname><given-names>D. F.</given-names></name><name xml:lang="ru"><surname>Ким</surname><given-names>Д. Ф.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Guturov</surname><given-names>S. I.</given-names></name><name xml:lang="ru"><surname>Гуторов</surname><given-names>С. Л.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gordeyev</surname><given-names>S. S.</given-names></name><name xml:lang="ru"><surname>Гордеев</surname><given-names>С. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow</institution></aff><aff><institution xml:lang="ru">ФГБУ РОНЦ им. Н.Н.Блохина РАМН, Москва</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2012-02-26" publication-format="electronic"><day>26</day><month>02</month><year>2012</year></pub-date><volume>1</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>31</fpage><lpage>34</lpage><history><date date-type="received" iso-8601-date="2015-02-27"><day>27</day><month>02</month><year>2015</year></date><date date-type="accepted" iso-8601-date="2015-02-27"><day>27</day><month>02</month><year>2015</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2012, Barsukov Y.A., Kim D.F., Guturov S.I., Gordeyev S.S.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2012, Барсуков Ю.А., Ким Д.Ф., Гуторов С.Л., Гордеев С.С.</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="en">Barsukov Y.A., Kim D.F., Guturov S.I., Gordeyev S.S.</copyright-holder><copyright-holder xml:lang="ru">Барсуков Ю.А., Ким Д.Ф., Гуторов С.Л., Гордеев С.С.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://onco-surgery.info/jour/article/view/37">https://onco-surgery.info/jour/article/view/37</self-uri><abstract xml:lang="en"><p>A rare case of multicomponental treatment of low-differentiated anal neuroendocrine cancer is presented. By using combined treatment involving chemotherapy, local hyperthermia and radiotherapy a complete response of recurrent neuroendocrine cancer has been achieved.A review of modern methods of diagnostics and treatment of rectal neurtoendocrine tumors is presented and possibilities of modern combined treatment are discussed.</p></abstract><trans-abstract xml:lang="ru"><p>Представлено редкое клиническое наблюдение нестандартного многокомпонентного лечения пациентки, страдающей низкодифференцированным нейроэндокринным раком анального канала. Благодаря использованию современных методов лечения, включающих химиотерапию, локальную гипертермию, лучевую терапию, удалось добиться полной клинической регрессии рецидиванейроэндокринного рака. В статье приводится краткий обзор современного состояния проблемы лечения нейроэндокринных опухолей прямой кишки, обсуждаются возможности использования многокомпонентных схем лечения.</p></trans-abstract><kwd-group xml:lang="en"><kwd>anal neuroendocrine cancer</kwd><kwd>combined treatment</kwd><kwd>local hyperthermia</kwd><kwd>chemotherapy</kwd><kwd>radiotherapy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>нейроэндокринный рак анального канала</kwd><kwd>комбинированное лечение</kwd><kwd>локальная гипертермия</kwd><kwd>химиотерапия</kwd><kwd>лучевая терапия</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Rosenberg J.L., Welch J.P. Carcinoid tumors of the colon. Ann J Surg 1985;149(6):775–9.</mixed-citation><mixed-citation xml:lang="ru">Rosenberg J.L., Welch J.P. Carcinoid tumors of the colon. 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