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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Surgery and Oncology</journal-id><journal-title-group><journal-title xml:lang="en">Surgery and Oncology</journal-title><trans-title-group xml:lang="ru"><trans-title>Хирургия и онкология</trans-title></trans-title-group></journal-title-group><issn publication-format="electronic">2949-5857</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">298</article-id><article-id pub-id-type="doi">10.17650/2686-9594-2019-9-3-54-58</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>CASE REPORT</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>КЛИНИЧЕСКОЕ НАБЛЮДЕНИЕ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Buschke-Lowenstein tumor: a case report</article-title><trans-title-group xml:lang="ru"><trans-title>Гигантская кондилома Бушке-Левенштейна (клиническое наблюдение)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1383-2925</contrib-id><name-alternatives><name xml:lang="en"><surname>Kolbashova</surname><given-names>Yu. N.</given-names></name><name xml:lang="ru"><surname>Колбашова</surname><given-names>Ю. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>1 Lubimova St., 153040 Ivanovo.</p></bio><bio xml:lang="ru"><p>Колбашова Юлия Николаевна.</p><p>153040 Иваново, ул. Любимова, 1.</p></bio><email>ykolbashova@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Aphanasyev</surname><given-names>D. V.</given-names></name><name xml:lang="ru"><surname>Афанасьев</surname><given-names>Д. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>1 Lubimova St., 153040 Ivanovo.</p></bio><bio xml:lang="ru"><p>153040 Иваново, ул. Любимова, 1.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Philosophov</surname><given-names>S. Yu.</given-names></name><name xml:lang="ru"><surname>Философов</surname><given-names>С. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>1 Lubimova St., 153040 Ivanovo.</p></bio><bio xml:lang="ru"><p>153040 Иваново, ул. Любимова, 1.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Burtsev</surname><given-names>V. V.</given-names></name><name xml:lang="ru"><surname>Бурцев</surname><given-names>В. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>1 Lubimova St., 153040 Ivanovo.</p></bio><bio xml:lang="ru"><p>153040 Иваново, ул. Любимова, 1.</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Ivanovo Regional Clinical Hospital</institution></aff><aff><institution xml:lang="ru">Ивановская областная клиническая больница</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2019-10-02" publication-format="electronic"><day>02</day><month>10</month><year>2019</year></pub-date><volume>9</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>54</fpage><lpage>58</lpage><history><date date-type="received" iso-8601-date="2019-10-01"><day>01</day><month>10</month><year>2019</year></date><date date-type="accepted" iso-8601-date="2019-10-01"><day>01</day><month>10</month><year>2019</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2019, ABV-press</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2019, АБВ-пресс</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="en">ABV-press</copyright-holder><copyright-holder xml:lang="ru">АБВ-пресс</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://onco-surgery.info/jour/about/editorialPolicies</ali:license_ref></license></permissions><self-uri xlink:href="https://onco-surgery.info/jour/article/view/298">https://onco-surgery.info/jour/article/view/298</self-uri><abstract xml:lang="en"><p>Buschke-Lowenstein tumor caused by human papilloma virus is a rare sexually transmitted disease of the anogenital region. Being histologically benign, clinically giant condyloma acuminatum exhibits malignant properties by adhering to surrounding tissues, and a high recurrence rate. However, no clear diagnostic criteria and surgical approach description has been detected for this condition. This clinical observation demonstrates a rare case of Buschke-Lowenstein tumor and the multi-stage surgical treatment, resulting in failure.</p></abstract><trans-abstract xml:lang="ru"><p>Гигантская кондилома Бушке-Левенштейна — редкое заболевание аногенитальной области, вызываемое вирусом папилломы человека, передающееся половым путем. Будучи гистологически доброкачественной, клинически гигантская кондилома проявляет злокачественные свойства, прорастая в окружающие ткани, отличается высокой вероятностью рецидива. Четких диагностических критериев и описания хирургической тактики при этом заболевании обнаружить не удалось. Данное клиническое наблюдение демонстрирует редкий случай гигантской кондиломы Бушке-Левенштейна и ее многоэтапное хирургическое лечение с неблагоприятным исходом.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Buschke-Lowenstein tumor</kwd><kwd>human papilloma virus</kwd><kwd>treatment</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>гигантская кондилома Бушке-Левенштейна</kwd><kwd>вирус папилломы человека</kwd><kwd>лечение</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Mrochkovski T.F., Millikan L.E., Parish L.Ch. Genital and perianal diseases. Translated from English. Ed. by Molochkov V.A. Moscow: GEOTAR-Media, 2019. 368 p. (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Мрочковски Т.Ф., Милликан Л.Э., Париш Л.Ч. Генитальные и перианальные заболевания. Пер. с англ. под ред. В.А. Молочкова. 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