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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Surgery and Oncology</journal-id><journal-title-group><journal-title xml:lang="en">Surgery and Oncology</journal-title><trans-title-group xml:lang="ru"><trans-title>Хирургия и онкология</trans-title></trans-title-group></journal-title-group><issn publication-format="electronic">2949-5857</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">268</article-id><article-id pub-id-type="doi">10.17650/2220-3478-2018-8-4-65-68</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>CASE REPORT</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>КЛИНИЧЕСКОЕ НАБЛЮДЕНИЕ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Successful treatment of rectal cancer complicated by bladder invasion, peritumorally abscess, and a fistula in the anterior abdominal wall (case report)</article-title><trans-title-group xml:lang="ru"><trans-title>Лечение больного раком прямой кишки с врастанием в мочевой пузырь, паратуморальным абсцессом, опухолевым свищом передней брюшной стенки (клинический случай)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3028-7578</contrib-id><name-alternatives><name xml:lang="en"><surname>Ivanov</surname><given-names>V. A.</given-names></name><name xml:lang="ru"><surname>Иванов</surname><given-names>В. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow 115478.</p></bio><bio xml:lang="ru"><p>Иванов Валерий Анатольевич.</p><p>115478 Москва, Каширское шоссе, 24.</p><p/></bio><email>dr.valeryivanov@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9303-8379</contrib-id><name-alternatives><name xml:lang="en"><surname>Gordeev</surname><given-names>S. S.</given-names></name><name xml:lang="ru"><surname>Гордеев</surname><given-names>С. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow 115478.</p></bio><bio xml:lang="ru"><p>115478 Москва, Каширское шоссе, 24.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8965-8172</contrib-id><name-alternatives><name xml:lang="en"><surname>Tkachev</surname><given-names>S. I.</given-names></name><name xml:lang="ru"><surname>Ткачев</surname><given-names>С. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow 115478.</p></bio><bio xml:lang="ru"><p>115478 Москва, Каширское шоссе, 24.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Perevoshchikov</surname><given-names>A. G.</given-names></name><name xml:lang="ru"><surname>Перевощиков</surname><given-names>А. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow 115478.</p></bio><bio xml:lang="ru"><p>115478 Москва, Каширское шоссе, 24.</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2018-12-27" publication-format="electronic"><day>27</day><month>12</month><year>2018</year></pub-date><volume>8</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>65</fpage><lpage>68</lpage><history><date date-type="received" iso-8601-date="2018-12-27"><day>27</day><month>12</month><year>2018</year></date><date date-type="accepted" iso-8601-date="2018-12-27"><day>27</day><month>12</month><year>2018</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2018, ABV-press</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2018, АБВ-пресс</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="en">ABV-press</copyright-holder><copyright-holder xml:lang="ru">АБВ-пресс</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://onco-surgery.info/jour/about/editorialPolicies</ali:license_ref></license></permissions><self-uri xlink:href="https://onco-surgery.info/jour/article/view/268">https://onco-surgery.info/jour/article/view/268</self-uri><abstract xml:lang="en"><p>This article reports the experience of treating a case of rectal cancer complicated by peritumorally abscess and intestinal fistulas in the anterior abdominal wall. Despite infectious complications, the patient underwent all stages of comprehensive treatment, including neoadjuvant chemoradiotherapy, consolidation polychemotherapy, and surgery. After sigmostomy with a course of antibacterial therapy, the patient received one cycle of external beam radiotherapy plus capecitabine followed by one full and one partial cycle of consolidating polychemotherapy (CapOx). Afterwards, the patient underwent R0 total mesorectal excision. No disease progression was observed during the next two years. Thus, complicated cancer require additional therapy; however, it should not be considered as a contraindication for combination treatment or as a reason for changing its order recommended in clinical guidelines.</p></abstract><trans-abstract xml:lang="ru"><p>В статье приводится пример комплексного лечения больного раком прямой кишки, осложненным паратуморальным абсцессом и кишечными свищами на передней брюшной стенке. Несмотря на наличие инфекционных осложнений, пациенту на фоне сопроводительной терапии были последовательно выполнены все этапы комплексного лечения: неоадъювантная химиолучевая терапия, консолидирующая полихимиотерапия и хирургическое лечение. Пациенту в рамках комплексного лечения рака прямой кишки после формирования сигмостомы по месту жительства под «прикрытием» антибактериальной терапии проведены 1 курс дистанционной химиолучевой терапии на фоне приема капецитабина, 1 полный и 1 неполный курс консолидирующей полихимиотерапии в режиме СарОх. Впоследствии пациенту выполнено хирургическое лечение — тотальная мезоректумэктомия в объеме R0. В течение 2 лет наблюдения прогрессирования заболевания не отмечено.</p><p>Таким образом, осложненное течение опухолевого процесса требует проведения сопроводительной терапии, однако не должно быть противопоказанием к проведению комплексного лечения и поводом для нарушения его последовательности, установленной в клинических рекомендациях.</p></trans-abstract><kwd-group xml:lang="en"><kwd>locally advanced rectal cancer</kwd><kwd>external intestinal fistula</kwd><kwd>abscess</kwd><kwd>chemoradiotherapy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>местно-распространенный рак прямой кишки</kwd><kwd>наружный кишечный свищ</kwd><kwd>абсцесс</kwd><kwd>химиолучевая терапия</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Gordeyev S.S., Ivanov V.A., Rasulov A.O. et al. Chemoradiotherapy in complicated locally advanced or recurrent rectal cancer treatment. 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