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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Surgery and Oncology</journal-id><journal-title-group><journal-title xml:lang="en">Surgery and Oncology</journal-title><trans-title-group xml:lang="ru"><trans-title>Хирургия и онкология</trans-title></trans-title-group></journal-title-group><issn publication-format="electronic">2949-5857</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">264</article-id><article-id pub-id-type="doi">10.17650/2220-3478-2018-8-4-30-33</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>LITERATURE REVIEW</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Epidemiology and statistics of anal cancer (literature review)</article-title><trans-title-group xml:lang="ru"><trans-title>Эпидемиология и статистика рака анального канала (обзор литературы)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Komarova</surname><given-names>L. E.</given-names></name><name xml:lang="ru"><surname>Комарова</surname><given-names>Л. Е.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow 115478.</p></bio><bio xml:lang="ru"><p>Комарова Людмила Егоровна.</p><p>115478 Москва, Каширское шоссе, 24.</p></bio><email>orgotdel@ronc.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Barsukov</surname><given-names>Yu. A.</given-names></name><name xml:lang="ru"><surname>Барсуков</surname><given-names>Ю. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow 115478.</p></bio><bio xml:lang="ru"><p>115478 Москва, Каширское шоссе, 24.</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2018-12-27" publication-format="electronic"><day>27</day><month>12</month><year>2018</year></pub-date><volume>8</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>30</fpage><lpage>33</lpage><history><date date-type="received" iso-8601-date="2018-12-27"><day>27</day><month>12</month><year>2018</year></date><date date-type="accepted" iso-8601-date="2018-12-27"><day>27</day><month>12</month><year>2018</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2018, Komarova L.E., Barsukov Y.A.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2018, Комарова Л.Е., Барсуков Ю.А.</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="en">Komarova L.E., Barsukov Y.A.</copyright-holder><copyright-holder xml:lang="ru">Комарова Л.Е., Барсуков Ю.А.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://onco-surgery.info/jour/article/view/264">https://onco-surgery.info/jour/article/view/264</self-uri><abstract xml:lang="en"><p>In recent decades, there has been a marked increase in the incidence of anal cancer. The main risk factors for anal cancer include human papillomavirus infection, promiscuity, homosexuality in men, positive Papanicolaou test, and smoking.</p></abstract><trans-abstract xml:lang="ru"><p>За последние десятилетия отмечается рост заболеваемости раком анального канала. Анализ показал, что развитие данной формы рака в большинстве случаев определяется такими факторами, как поражение вирусом папилломы человека, значительное число половых партнеров, половые взаимоотношения (гомосексуализм у мужчин), положительные результаты влагалищных мазков по Папаниколау, курение.</p></trans-abstract><kwd-group xml:lang="en"><kwd>anal cancer</kwd><kwd>human papillomavirus</kwd><kwd>risk factors</kwd><kwd>anal intraepithelial neoplasia</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак анального канала</kwd><kwd>вирус папилломы человека</kwd><kwd>факторы риска</kwd><kwd>анальная интраэпителиальная неоплазия</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>De Martel C., Ferlay J., Franceschi S. et al. Global Burden of Cancer attributable to infections in 2008: a review and synthetic analysis. Lancet Oncol 2.012;136(60):607—15. PMID: 22575588. 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