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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Surgery and Oncology</journal-id><journal-title-group><journal-title xml:lang="en">Surgery and Oncology</journal-title><trans-title-group xml:lang="ru"><trans-title>Хирургия и онкология</trans-title></trans-title-group></journal-title-group><issn publication-format="electronic">2949-5857</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">162</article-id><article-id pub-id-type="doi">10.17650/2220-3478-2016-6-1-22-26</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>ORIGINAL REPORTS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Features a combined surgical treatment in preserving the quality of life in patients with invasive colorectal cancer</article-title><trans-title-group xml:lang="ru"><trans-title>Возможности комбинированного хирургического лечения в сохранении качества жизни у пациенток с инвазивным раком прямой кишки</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Abduzhapparov</surname><given-names>S. B.</given-names></name><name xml:lang="ru"><surname>Абдужаппаров</surname><given-names>С. Б.</given-names></name></name-alternatives><address><country country="UZ">Uzbekistan</country></address><bio xml:lang="en"><p>383 Farobi St., Tashkent, 100179</p></bio><bio xml:lang="ru"><p>100179, Ташкент, ул. Фароби, 383</p></bio><email>sbab@inbox.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Matniyozova</surname><given-names>Sh. Ya.</given-names></name><name xml:lang="ru"><surname>Матниёзова</surname><given-names>Ш. Я.</given-names></name></name-alternatives><address><country country="UZ">Uzbekistan</country></address><bio xml:lang="en"><p>383 Farobi St., Tashkent, 100179</p></bio><bio xml:lang="ru"><p>100179, Ташкент, ул. Фароби, 383</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Republican Oncological Centre of Science at the Ministry of Health of Republic Uzbekistan</institution></aff><aff><institution xml:lang="ru">Республиканский онкологический научный центр Минздрава Республики Узбекистан</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2016-04-26" publication-format="electronic"><day>26</day><month>04</month><year>2016</year></pub-date><volume>6</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>22</fpage><lpage>26</lpage><history><date date-type="received" iso-8601-date="2016-04-25"><day>25</day><month>04</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-04-25"><day>25</day><month>04</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2016, ABV-press</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2016, АБВ-пресс</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="en">ABV-press</copyright-holder><copyright-holder xml:lang="ru">АБВ-пресс</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://onco-surgery.info/jour/about/editorialPolicies</ali:license_ref></license></permissions><self-uri xlink:href="https://onco-surgery.info/jour/article/view/162">https://onco-surgery.info/jour/article/view/162</self-uri><abstract xml:lang="en"><p><bold>Background.</bold> The aim of the work was to study the effect of combined surgical treatment of locally advanced rectal cancer (RC) with the invasion of the organs of the female reproductive system on the quality of life of patients.</p><p><bold>Materials and methods.</bold> Presents the diagnosis and treatment of 134 patients with the RC in age from 21 to 70 years, with the invasion of the organs of the female reproductive system. All patients carried the standard clinical and laboratory tests.</p><p><bold>Results.</bold> Half of the patients (50.7 % of cases) T4N1M0 stage of the disease has been diagnosed. In 75 (56.0 %) patients with tumor spread into the vagina, and in 16 (11.9 %) patients – just a few of the reproductive system. In the study group of 64 patients with the RC, along with surgery on the rectum, combined organ-performed surgery reproductive organs. In the control group all 70 patients was performed hysterectomy with appendages.</p><p><bold>Conclusions.</bold> Quality of life according to the questionnaire MENQOL, was significantly higher in patients with organ-treatment, which showed a decrease in vasomotor and psychological symptoms, as well as smoothing of irregularities in the physical and sexual spheres. Studies have show the validity of the widespread introduction in the oncological practice combined simultaneous operations that preserve the reproductive organs in women with invasive RC, which is especially important for women of reproductive age.</p></abstract><trans-abstract xml:lang="ru"><p/></trans-abstract><kwd-group xml:lang="en"><kwd>quality of life</kwd><kwd>invasive colorectal cancer</kwd><kwd>combined operations</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>качество жизни</kwd><kwd>инвазивный рак прямой кишки</kwd><kwd>комбинированные операции</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Бердов Б.А., Невольских A.A., Ерыгин Д.В., Титова Л.Н. Лечение местнораспространенного рака прямой кишки. Вопросы онкологии 2007;53(5):578–83. [Berdov B.А., Nevol’skikh A.A., Еrygin D.V., Тitovа L.N. Treatment of the locally spread colon cancer. Voprosy onkologii = Oncology Issues 2007;53(5):578–83. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Бердов Б.А., Невольских A.A., Ерыгин Д.В., Титова Л.Н. Лечение местнораспространенного рака прямой кишки. Вопросы онкологии 2007;53(5):578–83. [Berdov B.А., Nevol’skikh A.A., Еrygin D.V., Тitovа L.N. Treatment of the locally spread colon cancer. Voprosy onkologii = Oncology Issues 2007;53(5):578–83. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">2. Тулина И.А., Царьков П.В., Комкова Н.Е. Оценка безопасности комбинированных вмешательств при местно-распространенном раке прямой кишки в зависимости от преимущественного направления опухолевого роста. Вестник хирургической гастроэнтерологии 2010;(1):11–22. [Тulinа I.А., Tsar’kov P.V., Komkovа N.Е. Evaluation of the safety of combined interferences at the locally spread colon cancer depending on the preferred tumor direction. Vestnik khirurgicheskoy gastroenterologii = Herald of Surgical Gastroenterology 2010;(1):11–22. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Тулина И.А., Царьков П.В., Комкова Н.Е. Оценка безопасности комбинированных вмешательств при местно-распространенном раке прямой кишки в зависимости от преимущественного направления опухолевого роста. Вестник хирургической гастроэнтерологии 2010;(1):11–22. [Тulinа I.А., Tsar’kov P.V., Komkovа N.Е. Evaluation of the safety of combined interferences at the locally spread colon cancer depending on the preferred tumor direction. Vestnik khirurgicheskoy gastroenterologii = Herald of Surgical Gastroenterology 2010;(1):11–22. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">3. Барсуков Ю.А. Комбинированное и комплексное лечение больных раком прямой кишки. Рекомендации к лечению. М., 2011. [Barsukov Yu.А. Combined and comprehensive treatment of patients with colon cancer. Treatment recommendations. Мoscow, 2011. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Барсуков Ю.А. Комбинированное и комплексное лечение больных раком прямой кишки. Рекомендации к лечению. М., 2011. [Barsukov Yu.А. Combined and comprehensive treatment of patients with colon cancer. Treatment recommendations. Мoscow, 2011. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">4. Царьков П.В., Тулина И.А., Федоров Д.Н. и др. Отдаленные результаты хирургического лечения местно-распространенного рака прямой кишки с использованием экстрафасциального принципа выделения. Российский журнал гастроэнтерологии, гепатологии, колопроктологии 2010;20(4):75–82. [Tsar’kov P.V., Тulinа I.А., Fedorov D.N. et al. Afterhistory of the surgical treatment of the locally spread colon cancer with use of the extrafascial apportionment principle. Rossiyskiy zhurnal gastroenterologii, gepatologii, koloproktologii = Russian Journal of Gastroenterology, Hepatology, Coloproctology 2010;20(4):75–82. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Царьков П.В., Тулина И.А., Федоров Д.Н. и др. Отдаленные результаты хирургического лечения местно-распространенного рака прямой кишки с использованием экстрафасциального принципа выделения. Российский журнал гастроэнтерологии, гепатологии, колопроктологии 2010;20(4):75–82. [Tsar’kov P.V., Тulinа I.А., Fedorov D.N. et al. Afterhistory of the surgical treatment of the locally spread colon cancer with use of the extrafascial apportionment principle. Rossiyskiy zhurnal gastroenterologii, gepatologii, koloproktologii = Russian Journal of Gastroenterology, Hepatology, Coloproctology 2010;20(4):75–82. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">5. ХубезовД.А., ПучковК.В., КолесниковаН.О. Эффективность МРТ в дооперационном стадировании рака прямой кишки. Колопроктология 2009;28(2):38–41. [Hubezov D.А., Puchkov K.V., Kolesnikovа N.О. MRT efficiency in the pre-operation staging of the colon cancer. Koloproktologiya = Coloproctology 2009;28(2):38–41. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">ХубезовД.А., ПучковК.В., КолесниковаН.О. Эффективность МРТ в дооперационном стадировании рака прямой кишки. Колопроктология 2009;28(2):38–41. [Hubezov D.А., Puchkov K.V., Kolesnikovа N.О. MRT efficiency in the pre-operation staging of the colon cancer. Koloproktologiya = Coloproctology 2009;28(2):38–41. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">6. Caricato M., Borzomati D., Ausania F. et al. Prognostic factors after surgery for locally recurrent rectal cancer: an overview. Eur J Surg Oncol 2006;32(2):126–32.</mixed-citation><mixed-citation xml:lang="ru">Caricato M., Borzomati D., Ausania F. et al. Prognostic factors after surgery for locally recurrent rectal cancer: an overview. Eur J Surg Oncol 2006;32(2):126–32.</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">7. Hilditch J.R., Lewis J., Peter A. et al. A menopause-specific quality of life questionnaire: development and psychometric properties. Maturitas 1996;24(3):161–75.</mixed-citation><mixed-citation xml:lang="ru">Hilditch J.R., Lewis J., Peter A. et al. A menopause-specific quality of life questionnaire: development and psychometric properties. Maturitas 1996;24(3):161–75.</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">8. Chen S.L., Steele S.R., Eberhardt J. et al. Lymph node ratio as a quality and prognostic indicator in stage III colon cancer. Ann Surg 2011;253(1):82–7.</mixed-citation><mixed-citation xml:lang="ru">Chen S.L., Steele S.R., Eberhardt J. et al. Lymph node ratio as a quality and prognostic indicator in stage III colon cancer. Ann Surg 2011;253(1):82–7.</mixed-citation></citation-alternatives></ref></ref-list></back></article>
