Surgery and OncologySurgery and OncologyХирургия и онкология2949-5857Publishing House ABV Press12510.17650/2220-3478-2015-1-49-53ORIGINAL REPORTSОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯCHARACTERISTICS OF CLINICAL COURSE OF METASTATIC AND PRIMARY OVARIAN TUMORS IN COLON CANCERОСОБЕННОСТИ КЛИНИЧЕСКОГО ТЕЧЕНИЯ МЕТАСТАТИЧЕСКИХ И ПЕРВИЧНЫХ ОПУХОЛЕЙ ЯИЧНИКОВ ПРИ РАКЕ ТОЛСТОЙ КИШКИDzhanyanI. A.ДжанянИ. А.
Russian Federation

N.N. Blokhin Russian Cancer Research Center; 24 Kashirskoye Shosse, Moscow, 115478, Russia

 ФГБНУ «РОНЦ им. Н.Н. Блохина»; Россия, 115478, Москва, Каширское шоссе, 24

 

ikislichko@mail.ruKomarovI. G.КомаровИ. Г.
Russian Federation

N.N. Blokhin Russian Cancer Research Center; 24 Kashirskoye Shosse, Moscow, 115478, Russia

 ФГБНУ «РОНЦ им. Н.Н. Блохина»; Россия, 115478, Москва, Каширское шоссе, 24

 

PayanidiY. G.ПаянидиЮ. Г.
Russian Federation

N.N. Blokhin Russian Cancer Research Center; 24 Kashirskoye Shosse, Moscow, 115478, Russia

 ФГБНУ «РОНЦ им. Н.Н. Блохина»; Россия, 115478, Москва, Каширское шоссе, 24

 

N.N. Blokhin Russian Cancer Research CenterФГБНУ «РОНЦ им. Н.Н. Блохина»260520155149532605201526052015Copyright ©; 2015, Dzhanyan I.A., Komarov I.G., Payanidi Y.G.Copyright ©; 2015, Джанян И.А., Комаров И.Г., Паяниди Ю.Г.2015Dzhanyan I.A., Komarov I.G., Payanidi Y.G.Джанян И.А., Комаров И.Г., Паяниди Ю.Г.https://creativecommons.org/licenses/by/4.0https://onco-surgery.info/jour/article/view/125

The aim of this study was to investigate clinical pecuiliarities of ovarian tumors in colon cancer patients and determination of complex diagnostic methods.

Subject and methods. Russian N.N.  Blokhin Cancer Research Center archives were used for retrospective study, patients, who underwent treatment during 1989–2013  were included. Colon cancer patients with ovarian metastases and with synchronous or metachronous tumors were included.

Results. 141 patients were included: 91 patients had colon cancer with ovarian metastases (group 1) and 50 patients had synchronous or metachronous ovarian tumours (group 2). Ovarian tumors were diagnosed during the 1 year in 74 (81.3 %) patients in group 1 and in 23 (46 %) in group 2. Patients in group 2 less frequently had children (9 (18.0 %) vs 5 (5.5 + 2.3 %), р < 0.05), family history of cancer (3 (6 %) vs 16 (17.6 %), р < 0.05) and concomitant diseases. Median CA 125 level in group 1 was 64.96 ng/ml and 180 ng/ml in group 2. Ovarian tumors had solid and cystic structure during US examination in 66 (73 %) patients in group 1 and 31 (62 %) patients in group 2 had solid ovarian tumors on US examination.

Conclusions. The differential diagnostics of primary and metastatic ovarian tumors must include CEA, CA 19–9 and CA 125 serum levels and pelvic US.

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