Comparative analysis of short-term and long-term outcomes after surgical treatment of sigmoid colon cancer and rectosigmoid junction cancer: single-center retrospective cohort study

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Abstract

Background. Distinguishing rectosigmoid colon cancer as a separate nosological entity does not affect the choice of modern treatment strategy.

Aim. To evaluate differences in short-term and long-term oncological outcomes of surgical treatment for sigmoid colon cancer (SCC) and rectosigmoid colon cancer (RSCC).

Materials and methods. This single-center retrospective cohort study included patients with RSCC and SCC who underwent radical surgical treatment between January 2019 and December 2023. The primary endpoints were the rate of grade IIIB and higher complications per the Clavien–Dindo classification, anastomotic leak rate, recurrence rate, and 3-year overall survival and disease-free survival.

Results. The study included 50 patients with RSCC and 137 patients with SCC. The rates of grade IIIB and higher complications were 2 (4 %) and 9 (6.6 %), p = 0.115; the rates of colorectal anastomotic leak were 4 (8 %) and 4 (2.9 %), p = 0.213, respectively. Three-year overall survival was 84.6 % and 85.6 % (p = 0.856); 3-year disease-free survival was 72.8 % and 81.8 % (p = 0.227), respectively.

Conclusion. Within the framework of this retrospective analysis, no clinically significant differences were found in short-term and long-term treatment outcomes for sigmoid colon cancer and rectosigmoid colon cancer.

About the authors

Maksim D. Sivolob

S.S. Yudin Moscow City Clinical Hospital, Moscow Healthcare Department; 2 I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)

Author for correspondence.
Email: maksim-sivlb@rambler.ru
ORCID iD: 0000-0001-8773-7475
Russian Federation, 4 Kolomenskiy Proezd, Moscow, 115446; Build. 2, 8 Trubetskaya St., Moscow, 119048

D. V. Erygin

S.S. Yudin Moscow City Clinical Hospital, Moscow Healthcare Department

Email: maksim-sivlb@rambler.ru
ORCID iD: 0000-0002-7278-8525
Russian Federation, 4 Kolomenskiy Proezd, Moscow, 115446

S. B. Polikarpova

I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)

Email: maksim-sivlb@rambler.ru
ORCID iD: 0000-0003-3621-7394
Russian Federation, Build. 2, 8 Trubetskaya St., Moscow, 119048

M. S. Lebed’ko

S.P. Botkin Moscow Multidisciplinary Scientific and Clinical Center, Moscow Healthcare Department

Email: maksim-sivlb@rambler.ru
ORCID iD: 0000-0002-3987-9361
Russian Federation, 5 2nd Botkinskiy Proezd, Moscow, 125284

D. A. Sinyutin

S.S. Yudin Moscow City Clinical Hospital, Moscow Healthcare Department

Email: maksim-sivlb@rambler.ru
ORCID iD: 0009-0006-6537-1103
Russian Federation, 4 Kolomenskiy Proezd, Moscow, 115446

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