Assessing the impact of gender and age differences on overall survival of patients with colorectal cancer

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Abstract

Introduction. Recent studies have led to the conclusion that gender is an important factor influencing the prognosis of survival of patients with colorectal cancer.

Aim. To analyze 5-year overall survival rates in patients with colorectal cancer of different sexes and in different age groups.

Materials and methods. The study included 1593 patients, of whom 720 were men (45.2 %) and 873 women (54.8 %). Patients were divided into 3 age groups: under 50 years, 50–70 years and over 70. Overall survival rates were calculated, followed by comparison between groups of patients, taking into account gender and stage of the disease.

Results. Analysis of treatment results taking into account a gender approach showed that the prognosis of the disease was most favorable in women. With approximately the same 5-year survival rate in men and women (54.9 and 52.7 %), this indicator correlated with the age of the patients and was significantly better than in men in the group of patients under 50 years of age.

Conclusion. The identified gender and age characteristics in the development and course of colorectal cancer are relevant for oncologists when choosing diagnostic, treatment and rehabilitation strategies. 

About the authors

B. I. Gataullin

Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University; Kazan State Medical Academy – branch of Russian Medical Academy of Continuing Professional Education, Ministry of Health
of Russia

Author for correspondence.
Email: bulatg@list.ru
ORCID iD: 0000-0003-1695-168X

74 K. Marks St., Kazan 420012; 36 Butlerova St., Kazan 420012

Russian Federation

I. G. Gataullin

Kazan State Medical Academy – branch of Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia

Email: fake@neicon.ru
ORCID iD: 0000-0002-6707-6750

36 Butlerova St., Kazan 420012

Russian Federation

R. G. Biktemirova

Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University

Email: fake@neicon.ru
ORCID iD: 0000-0002-0416-5342

74 K. Marks St., Kazan 420012

Russian Federation

Ya. A. Erpert

Kazan State Medical Academy – branch of Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia

Email: fake@neicon.ru
ORCID iD: 0009-0007-0937-928X

36 Butlerova St., Kazan 420012

Russian Federation

N. F. Didakunan

Kazan State Medical University of Ministry of Health of Russia

Email: fake@neicon.ru
ORCID iD: 0000-0002-9852-2071

49 Butlerova St., Kazan 420012

Russian Federation

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