КОРОТКИЙ КУРС ПРЕДОПЕРАЦИОННОЙ ЛУЧЕВОЙ ТЕРАПИИ В КОМБИНАЦИИ С ХИМИОТЕРАПИЕЙ, ЛОКАЛЬНОЙ ГИПЕРТЕРМИЕЙ И ПРОЛОНГИРОВАННЫМ ИНТЕРВАЛОМ ДО ОПЕРАЦИИ В ЛЕЧЕНИИ РАКА ПРЯМОЙ КИШКИ: ИССЛЕДОВАНИЕ II ФАЗЫ

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А. О. Расулов

Российский онкологический научный центр им. Н.Н. Блохина Минздрава России

Email: fake@neicon.ru
Россия

С. С. Гордеев

Российский онкологический научный центр им. Н.Н. Блохина Минздрава России

Автор, ответственный за переписку.
Email: ss.netoncology@gmail.com

Контакты: Сергей Сергеевич Гордеев - ФГБУ РОНЦ им. Н.Н. Блохина Минздрава России, 115478 Москва, Каширское шоссе, 23 

Россия

В. А. Иванов

Российский онкологический научный центр им. Н.Н. Блохина Минздрава России

Email: fake@neicon.ru
Россия

Ю. А. Барсуков

Российский онкологический научный центр им. Н.Н. Блохина Минздрава России

Email: fake@neicon.ru
Россия

А. Г. Малихов

Российский онкологический научный центр им. Н.Н. Блохина Минздрава России

Email: fake@neicon.ru
Россия

А. Б. Байчоров

Российский онкологический научный центр им. Н.Н. Блохина Минздрава России

Email: fake@neicon.ru
Россия

С. И. Ткачёв

Российский онкологический научный центр им. Н.Н. Блохина Минздрава России

Email: fake@neicon.ru
Россия

Е. Н. Козак

Российский онкологический научный центр им. Н.Н. Блохина Минздрава России

Email: fake@neicon.ru
Россия

Список литературы

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  2. Fokstuen T., Holm T., Glimelius B. Postoperative morbidity and mortality in relation to leukocyte counts and time to surgery after short-course preoperative radiotherapy for rectal cancer. Radiother Oncol 2009;93(2):293–7. doi: 10.1016/j.radonc.2009.08.034.
  3. Pettersson D., Glimelius B., Iversen H. et al. Impaired postoperative leucocyte counts after preoperative radiotherapy for rectal cancer in the Stockholm III Trial. Br J Surg 2013;100(7):969–75.
  4. Ceelen W., Fierens K., Van Nieuwenhove Y., Pattyn P. Preoperative chemoradiation versus radiation alone for stage II and III resectable rectal cancer: a systematic review and meta-analysis. Int J Cancer 2009;124(12):2966–72. doi: 10.1002/ijc.24247.
  5. Shin S.J., Yoon H.I., Kim N.K. et al. Upfront systemic chemotherapy and preoperative short-course radiotherapy with delayed surgery for locally advanced rectal cancer with distant metastases. Radiat Oncol 2011;6:99. doi: 10.1186/1748-717X-6-99.
  6. Beppu N., Matsubara N., Kakuno A. et al. Feasibility of modified short-course radiotherapy combined with a chemoradiosensitizer for T3 rectal cancer. Dis Colon Rectum 2015;58(5):479–87. doi: 10.1097/DCR.0000000000000323.
  7. Kerr S.F., Norton S., Glynne-Jones R. Delaying surgery after neoadjuvant chemoradiotherapy for rectal cancer may reduce postoperative morbidity without compromising prognosis. Br J Surg 2008;95(12):1534–40. doi: 10.1002/bjs.6377.
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  9. Барсуков Ю.А., Ткачев С.И., Кныш В.И. и др. Комбинированное лечение рака прямой кишки с использованием полирадиофикации. Вопросы онкологии 2008;54(3):350–3. [Barsukov Yu.A., Tkachev S.I., Knysh V.I. et al. Combined treatment for rectal cancer using different radiomodification means. Voprosy onkologii = Problems in Oncology 2008;54(3):350–3. (In Russ.)].
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  12. Yeo S.G., Oh J.H., Kim D.Y. et al. Preoperative short-course concurrent chemoradiation therapy followed by delayed surgery for locally advanced rectal cancer: a phase 2 multicenter study (KROG 10-01). Int J Radiat Oncol Biol Phys 2013;86(1):34–9. doi: 10.1016/j.ijrobp.2012.11.018.
  13. Bujko K., Nowacki M.P., Nasierowska-Guttmejer A. et al. Long-term results of a randomized trial comparing preoperative short-course radiotherapy with preoperative conventionally fractionated chemoradiation for rectal cancer. Br J Surg 2006;93(10):1215–23.
  14. Gerard J.P., Conroy T., Bonnetain F. et al. Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3–4 rectal cancers: results of FFCD 9203. J Clin Oncol 2006;24(28):4620–5.
  15. Pettersson D., Holm T., Iversen H. et al. Preoperative short-course radiotherapy with delayed surgery in primary rectal cancer. Br J Surg 2012;99(4):577–83. doi: 10.1002/bjs.7796.
  16. Overgaard J. Hypoxic radiosensitization: adored and ignored. J Clin Oncol 2007;25(26):4066–74.
  17. Wasserberg N. Interval to surgery after neoadjuvant treatment for colorectal cancer. World J Gastroenterol 2014;20(15):4256–62. doi: 10.3748/wjg.v20.i15.4256.
  18. Evans J., Tait D., Swift I. et al. Timing of surgery following preoperative therapy in rectal cancer: the need for a prospective randomized trial? Dis Colon Rectum 2011;54(10):1251–9. doi: 10.1097/DCR.0b013e3182281f4b.
  19. Sloothaak D.A., Geijsen D.E., van Leersum N.J. et al. Optimal time interval between neoadjuvant chemoradiotherapy and surgery for rectal cancer. Br J Surg 2013;100(7):933–9. doi: 10.1002/bjs.9112.
  20. Petrelli F., Sgroi G., Sarti E., Barni S. Increasing the Interval Between Neoadjuvant Chemoradiotherapy and Surgery in Rectal Cancer: A Meta-Analysis of Published Studies. Ann Surg 2016;263(3):458–64. doi: 10.1097/SLA.0000000000000368.
  21. Beppu N., Matsubara N., Noda M. et al. The timing of surgery after preoperative shortcourse S-1 chemoradiotherapy with delayed surgery for T3 lower rectal cancer. Int J Colorectal Dis 2014;29(12):1459–66. doi: 10.1007/s00384-014-1997-5.
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  23. Faria S., Kopek N., Hijal T. et al. Phase II trial of short-course radiotherapy followed by delayed surgery for locoregionally advanced rectal cancer. Colorectal Dis 2014;16(2): O66–70. doi: 10.1111/codi.12466.
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  25. Aschele C., Cionini L., Lonardi S. et al. Primary tumor response to preoperative chemoradiation with or without oxaliplatin in locally advanced rectal cancer: pathologic results of the STAR-01 randomized phase III trial. J Clin Oncol 2011;29(20):2773–80. doi: 10.1200/JCO.2010.34.4911.
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  27. De Haas-Kock D.F., Buijsen J., Pijls-Johannesma M. et al. Concomitant hyperthermia and radiation therapy for treating locally advanced rectal cancer. Cochrane Database Syst Rev 2009;8(3):CD006269. doi: 10.1002/14651858.CD006269.pub2.
  28. Shoji H., Motegi M., Osawa K. et al. A novel strategy of radiofrequency hyperthermia (neothermia) in combination with preoperative chemoradiotherapy for the treatment of advanced rectal cancer: a pilot study. Cancer Med 2015;4(6):834–43. doi: 10.1002/cam4.431.
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