Email this article RADIORESISTANCE OF THE TUMOR AND ITS SOLUTIONS (LITERATURE REVIEW)
- Authors: Barsukov Y.A.1, Malikhov A.G.1, Tkachev S.I.1, Kuzmichev D.V.1
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Affiliations:
- N.N. Blokhin Russian Cancer Research Center
- Issue: Vol 5, No 1 (2015)
- Pages: 9-19
- Section: REVIEW
- Published: 26.05.2015
- URL: https://onco-surgery.info/jour/article/view/120
- DOI: https://doi.org/10.17650/2220-3478-2015-1-9-19
- ID: 120
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Abstract
Presented article is a review of domestic and foreign literature on the application of radiomodifying drugs with electron-affinic properties (metronidazole and its derivatives) with the aim of increasing the effectiveness of radiation therapy. The mechanism of action and properties of the electron-affinic drugs of is described. Special attention is paid to the creation of a new medicinal form of metronidazole with the hydrogel-based biopolymer and its inclusion in combined treatment of resectable and locally advanced rectal cancer.
About the authors
Yu. A. Barsukov
N.N. Blokhin Russian Cancer Research Center
Author for correspondence.
Email: u_barsukov@mail.ru
N.N. Blokhin Russian Cancer Research Center; 24 Kashirskoye Shosse, Moscow, 115478, Russia
Russian FederationA. G. Malikhov
N.N. Blokhin Russian Cancer Research Center
Email: fake@neicon.ru
N.N. Blokhin Russian Cancer Research Center; 24 Kashirskoye Shosse, Moscow, 115478, Russia Russian Federation
S. I. Tkachev
N.N. Blokhin Russian Cancer Research Center
Email: fake@neicon.ru
N.N. Blokhin Russian Cancer Research Center; 24 Kashirskoye Shosse, Moscow, 115478, Russia Russian Federation
D. V. Kuzmichev
N.N. Blokhin Russian Cancer Research Center
Email: fake@neicon.ru
N.N. Blokhin Russian Cancer Research Center; 24 Kashirskoye Shosse, Moscow, 115478, Russia Russian Federation
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